Piperacillin and Tazobactam for Injection
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چکیده
CLINICAL PHARMACOLOGY Adults Peak plasma concentrations of piperacillin and tazobactam are attained immediately after completion of an intravenous infusion of Piperacillin and Tazobactam for Injection. Piperacillin plasma concentrations, following a 30 minute infusion of Piperacillin and Tazobactam for Injection, were similar to those attained when equivalent doses of piperacillin were administered alone, with mean peak plasma concentrations of approximately 134, 242 and 298 mcg/mL for the 2.25 g, 3.375 g and 4.5 g Piperacillin and Tazobactam for Injection doses, respectively. The corresponding mean peak plasma concentrations of tazobactam were 15, 24 and 34 mcg/mL, respectively.
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